Anxiety Treatment Medications Psychotherapy and medication may help those suffering from anxiety disorders. Benzodiazepines such as Xanax, Klonopin, and Valium are used to treat anxiety. Antidepressants can also help with anxiety. SSRIs such as citalopram (Celexa) and fluoxetine (Prozac) are effective in preventing neurons in the brain from absorbing serotonin,